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No significant effect of child's first language or socio-economic status was found but children with weaker memory skills demonstrated stronger learning gains.
But rats given propranolol froze only about half as often, indicating a weaker memory for the fearful association between sound and shock.
Not so for the injected rats: They showed about one-fourth the freezing behavior of uninjected rats, indicating a much weaker memory, Miller and Sweatt report online today in Neuron.
AAV-IGF1-treated mice showed weaker memory enhancement (Fig 1E).
Post-hoc analysis revealed that CRND8 mice showed a weaker memory than their nTg controls at each age of testing (t(25) = 3.2, P < 0.01, t(26) = 3.4, P < 0.01, and t(16) = 5.4, P < 0.001, for three-, six-, and 12 month-old age cohorts, respectively, Figure 1C, right panel).
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They were also less prone to freeze up in response to events that would normally induce fear, such as seeing cats.In addition to this lack of instinctive fear, the knock-out mice seemed to have weaker memories for past aversive experiences.
The mutant mice also appear to have weaker memories of scary encounters than normal mice do.
Slow-wave activity during sleep may help strengthen neural connections and provide memories with long-term stability, in which case decreased slow-wave activity in older adults could contribute to their weaker memories.
The temporal dynamics of memory reconsolidation depend on the strength and age of the memory, such that younger and weaker memories are more easily reconsolidated than older and stronger ones [34].
Reviewer 1: 1) It has been shown that the reaction time of respondents differs between strong and weak memories with weaker memories having longer reaction times (i.e. Stark and Squire, 2000).
Each time you do that, you will make yourself better at extracting weaker memories back into your consciousness making it easier to learn formulae in the future.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com