Repeated drug administration triggers neuroplastic changes in glutamatergic inputs to the striatum and midbrain dopamine neurons, enhancing the brain's reactivity to drug cues, reducing the sensitivity to non-drug rewards, weakening self-regulation, and increasing the sensitivity to stressful stimuli and dysphoria.
More specifically, the presence of additional ions upon the introduction of the dye species results in an increase in the solution conductivity with increasing dye concentration, which in turn results in the ions weakening self-electrophoresis through a decrease in the inner electric field with increasing solution conductivity [55].
Of course, if really have diarrhea, this may not be of any consolation to your weakened self!
As a kind of negative interpersonal experience, it can bring emotional exhaustion and depression, weaken self-regulatory resources (Ferris et al., 2015; Wu et al., 2012), reduce job satisfaction, job performance and organizational citizenship behaviors, and raise deviant behaviors and turnover intention (Ferris et al., 2008; Ferris et al., 2015).
Taking others' perspective may weaken self-referential processes and induce decreased vMPFC activity.
As shown for SLK, activation segment phosphorylation weakens self-association.
The association between being 75 or older and a weakening self-estimated PCS has been demonstrated in other studies [ 29].
Beyond the risks of sectarian slaughter, there's the prospect that other countries in the region will be quick to assert their influence, further weakening Iraqi self-governance.
This self-weakening, self-defeating attitude is adopted by those who claim to "defend Israel" by undermining the credibility of the new testimonies from Operation Cast Lead.
He felt direct government relief payments would weaken moral character, undermine self-respect and discourage personal initiative.
The thought behind "psychological integration" is that a lack of it is weakening to the self.
