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Some writers defend a less austere version of this model, by weakening the notion of validity.
At the third and final level, dropout may contribute to a weakening of the internal validity; ie, dropout may cause, that the observed differences between the compared groups, may not be attributed only to the hypothesized effect under investigation.
The study employed measures of feasibility and discomfort that were not validated which weakens the validity of the conclusions.
The availability of denser and denser SNP panels weakens the validity of the assumption of linkage equilibrium; almost every two nearby markers are dependent.
Mechanics experienced significant historical changes in job duties that weaken the validity of extrapolation of current exposure to historical estimates.
We used the risk estimates from analyses that excluded mechanics because in the study by Garshick et al. (2012) mechanics experienced significant historical changes in job duties that weakened the validity of extrapolation of the current exposure to historical estimates.
Studies have shown that psycho-educational interventions may improve PDwS and primary caregivers' outcomes, but many of the published RCTs have significant methodological shortcomings which limit the comparability of studies and weaken the validity of the conclusions drawn about their effectiveness.
This represents loss of valuable information and may weaken the validity of the findings.
This improvement at the group level failed to achieve the lower bound of the minimal CID range established by our current study, which may weaken the validity of the study conclusion about the effect of the self-management education on the quality of self-care after stroke.
Because the most important results in this study are from ages <50 years, the lack of information on postmenopausal hormone therapy or body weight does not weaken the validity of the findings.
Lastly, some of the results were based on a random-effect model that might weaken the validity of the analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com