Aging is a gradual process of morphologic and physiologic changes that naturally predisposes older adults to progressive weakening, functional decline, morbidity, disability, poor quality of life, and increased mortality.
Selective harvesting of certain species of acacia threatened both forages for livestock, especially the browsers (e.g. goats and camels), and weakened the ecological insurance (functional redundancy and response diversity) that the harvested species provide during extreme weather events (Walker et al. 2004; Kahmen et al. 2005).
Therefore, we considered that increased AS could be a result of inaccurate splicing, which could weaken the function of the corresponding genes by decreasing the functional transcripts.
5 Advancing age brings a natural gradual weakening of functional capacity and a progressive decrease in physiologic reserve capacity leading to permanent deficits of physical function and psychomotor efficiency.
However, adjustment for parental stress only slightly weakened the association between wheezing and functional constipation.
That is, the functional support between generations is not weakened by spatial distance.
Extrapolating this to our weakened cohort could explain how significant group differences in functional capacity were found despite group differences in QFM strength being statistically non-significant.
Functional electrical stimulation (FES) is one of these methods, which aims to stimulate the nerves of the weakened muscles so that the resulting muscle contractions resemble those of a functional task.
By surveying CYP1A2 polymorphisms in total 91 M. fascicularis and M. mulatta, we found several null alleles segregating in these species, indicating functional constraint on CYP1A2 in macaques may have weakened after the divergence between humans and macaques.
It is known that paralogues undergo functional diversification, which tends to be accompanied by a weakened selection and the acceleration of sequence evolution [ 43].
