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The relative weak viability of this knockdown cells could have been outcompeted by other shRNA clones against proteins which function was less cytotoxic for the cell.
Because of the weak viability of dlp f03537 homozygotes, only heterozygotes were generated in sufficient numbers for the sedation assays.
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Silencing all these kinases, except MAP2K7, induced a weaker viability phenotype in the MSC preparations compared with fibroblasts, suggesting that disruption of the BCR signaling pathway could either be compensated for by the MSCs or that the pathway was not essential for their survival.
In summary, we conducted a detailed study of the effects of weak DC on viability, gene expression and morphology of B. subtilis.
The weak inhibition of viability after reduction of HSPA8 expression was unexpected considering the log2 ratios from HSPA8-A (-0.885, p = 2.0e-5) and HSPA8-B (-0.446, p = 3.2e-2).
As shown in Figure 4, Doxy induces a very weak increase in cell viability at 24 h and reduces the viability rate slightly after 48 h in parental BJAB and BJAB-Tet cells.
The various measures have not spurred private investment in the recipient countries, and their economic viability is weak.
While JNK inhibitors had only a weak effect on cell viability, inhibition of MEK and p38 affected cell proliferation, but independent of IR (i.e., similar effect in treated and untreated cells).
Centrioles are lost due to damage of the CENPJ orthologue dsas-4 in Drosophila; in contrast, the knockout flies can live until adulthood but have weak coordination and lower viability [ 65].
The cells on ZnO NWs showed weaker adhesion and lower viability than cells on a flat ZnO substrate.
Both PIK3CA2 and MAP3K9 were associated with weaker reduction in cell viability compared with the CTG-based re-tests (Fig. 3).
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