Sentence examples for weak to potent from inspiring English sources

All of the synthesized compounds displayed weak to potent PTP1B inhibitory activities (5.62 96.25%) at 20 μg/mL.

In vertebrates, pairs of Hsd enzymes participate in a prereceptor regulatory system of steroid action through the interconversion of weak to potent hormones (Penning 2003).

Akr1b enzymes that convert glucose to sorbitol can also reduce retinal to retinol (Ruiz et al. 2009), and some Akr1c enzymes can act as Hsd enzymes controlling the interconversion of weak steroid hormones to potent hormones (Dufort et al. 1999).

While the search for ligands for some target classes of the epigenetic targets is difficult because of low hit rates from high- and medium-throughput screening, often, weak hits can be optimized to potent, selective probe molecules.

Additionally, while these modifications discourage ligands with weak to moderate affinity for the ATP site, they can also promote the identification of potent ATP-competitive inhibitors.

It feels weak to cough.

Also, DNA repair, apoptosis, immunosurveillance mechanisms, usually discounted in risk assessment, are effective particularly when the frequency of genetic events is low (related to weak potency of OTA as opposed to cellular responses to potent mutagens which would be overwhelming).

Follicular cell function depends on various molecular factors: (1) the level of DHT; (2) the presence of active AR; (3) the biotransformation of dehydroepiandrosterone (DHEA) and other weak androgens to more potent androgens such as testosterone or DHT by 5α-reductase; (4) the low enzymatic activity of androgen-inactivating enzymes.

For example, in occupational studies, exposures and relative risks may be higher while differences in lifestyle factors between different groups of workers are smaller (Checkoway et al. 2004); thus, any confounding by nonoccupational factors is likely to be weak, even from potent causes of cancer such as cigarette smoking (Siemiatycki et al. 1988).

Molecular modeling techniques such as 2D-QSAR and 3D-QSAR analysis were applied to establish models to distinguish potent and weak CETP inhibitors.

Phagocytosis is not required for the host defense against the weak Gram-negative pathogen E. coli but is required against both weak and potent Gram-positive pathogens ([16], this work).