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Immunoreactivity was evaluated for staining intensity (none, weak, intense) and extent (none, <10%; heterogeneous, 10 50%; homogeneous, ⩾50%) of each tumour.
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The intensity of these reactions was expressed by indices of positivity: 0, 1, 2, 3, 4, and 5, indicating, respectively, barely positive, positive, weak, moderate, intense, and very intense reactions.
Sporadic staining of positive stromal cells, including endothelial cells, was localised to the cytoplasm and ranged in intensity from weak to intense.
We previously developed the AIRmax and AIRmin mouse lines by phenotypically selecting, from a heterogeneous population, mice that had either an intense or a weak acute inflammatory response (AIR) [ 6].
The staining intensity was scored as weak or intense and for SR-B1 also as negative in a few cases.
Importantly, addition to the solution of an electron acceptor causes large drop of the photocurrent both under weak and intense UV illumination generated by an argon-ion laser.
He was weak from intense training and caring for his wife, and the pressures of the Olympic Trials was equally as draining.
The epithelial staining of SR-B1 and HMG-CoA reductase was more heterogeneous, ranging from weak to intense (Table 2).
MIC1 expression was considered positive if more than 25% of cells showed weak to intense staining within each cylinder.
In contrast to the bHPA method, iHPA showed heterogenous weak to intense (+++; PTs) or weak to moderate labelling of MeWo cells.
Both intratumoral and intrastromal FOXP3+CD3+ cells were present in the patients tissues and the expression level of FOXP3 in the intratumoral Tregs ranged from weak to intense.
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