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The development of composite hydrogels has provided a versatile alternative approach for improving the strength of hydrogels via the use of a stiff second network that reinforces the weak hydrogel network, or via the incorporation of particles in the hydrogel matrix.
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In conclusion, by taking advantage of the characteristics of natural polymers such as chitosan, alginate, and carrageenan, the drug release can be modulated by taking into consideration the ability of the polymers to form strong or weak hydrogel networks.
FTIR was used to evaluate the types of functional groups present in the hydrogel networks and the composition of the hydrogels, and to confirm the successful loading of the drugs to the hydrogel network.
Its inclusion could lead to a modification of the hydrogel network, affecting release.
The results tend to show that a thermo-sensitive weak hydrogel is formed by the polyampholyte while a stiff, but fragile, hydrogel is formed by the telechelic polyelectrolyte.
E.coli were patterned and cultured in an interconnected three-dimensional (3D) hydrogel network.
This method of sequential addition was used so that the siRNA is entrapped in the interpenetrating (IPN) dextran hydrogel network.
In addition, to further improve the mechanical robustness of the hydrogel network, composite hybrid hydrogels provide an additional mechanical reinforcement.
Consequently, intermolecular and intramolecular attraction were suppressed leading to inhibition of xanthan hydrogel network formation.
Moreover, with the addition of fGO to GelMA, mechanical strength of the hydrogel network was enhanced.
Hydrogel network hydrophobicity, which promotes protein adsorption, consequently can influence cell adhesion.
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