It appears that leatherbacks have adopted a regional rather than a local optimum for nest placement patterns, possibly resulting from their weak beach fidelity and the frequent erosion and destruction of their nesting beaches.
That, he said, is, "Fidelity, fidelity, fidelity".
In this study, human cells expressing DNA polymerase ζ (Pol ζ) variants with low fidelity or weak catalytic activity have been established with Nalm-6-MSH+ cells and their sensitivity to mutagenicity and cytotoxicity of benzo[a]pyrene diol epoxide (BPDE) and ultraviolet-C light (UV-C) was examined.
If fidelity is weak, clinical supervision is given for the next session, followed by a further independent observation.
The ability of these polymerases to catalyze TLS, however, is associated with an increased frequency of mutation because of the lack of 3′ 5′ exonuclease proofreading activity, weak processivity, and low fidelity.
Thus courage, self-sacrifice, self-control and fidelity were prized, but the weak might be expelled to enable the tribe's survival (Darwin 1871, p. 96, 77).
Both thin and thick aerofoils are considered and the low-fidelity results agree well with the high-fidelity ones for the case of weak gust and attached aerodynamic flow, whereas the opposite is true for the case of strong gust and separated aerodynamic flow.
Belief in a benevolent cosmic order contends with fidelity to the cruel Darwinian maxim that "the weak are meat the strong do eat".
Neither mutual specificity nor mutual fidelity is possible with the basic architecture and weak activation; thus, some sort of insulating mechanism is required to obtain MFMS for weakly-activated pathways [ 22].
