Cohort effects seemed to explain more than period effects, and a weak downward trend starting with women born in 1883-92 was noted.
The results, shown in Figure 6, reveal strong upward shifts in the p Ka of D407 (in the O conformation), D408 O), E346(T) and D924(T), and a weak downward shift in K940(O), thus confirming that these side-chains are most likely protonated in those protomer states.
A regression analysis of the association between calendar year of diagnosis and 25-OHD level showed a weak downward trend during 1973 2007 of 0.07 nmol/L per year.> -wrap-foot> * Negative value means before and positive means after diagnosis During the follow-up period, 399 patients died, of whom 343 (86%) from cancer.
The rise in wind shear appears to be associated with "a weak but robust downward trend in U.S. landfalling hurricanes".
June's already weak report was revised downward, to 78,000 jobs from 112,000.
Mr. Hollande has said he wants to move Europe in a new direction, one in which countries continue to mend their finances to strengthen their foundations for the future, but avoid the drastic spending cuts that have extended the long-running euro crisis by pushing Greece, Spain and other weak countries into a downward spiral.
Data from the small, business-tracking National Federation of Independent Businesses is more in line with the results from the Adaptive Planning poll, finding that owners remain skeptical of the recovery amid a weak labor market, challenging downward pressure on pricing and continued difficulties in obtaining credit.
Mutations in genes encoding the tasiRNA biosynthesis components lead to similar phenotypic consequences that are generally weak, including the slight downward curling of rosette leaves and the precocious initiation of trichomes on the abaxial (lower) side of young leaves, also known as accelerated vegetative phase change [16].
Economists worry that a weakening job market will translate into less spending, which could deliver a downward spiral: weaker investment as sales dry up, and less hiring.
The result is that C and D malls get even weaker, with B malls potentially slipping into the C and D category, and even the A malls struggling to attract new tenants, who will demand more concessions from the mall operators, who then get weaker and so a downward cycle goes.
It is a way of behaving such that one takes actions, conscious or unconscious, to keep those of other races pressed downward into weaker states of power and lesser states of freedom, with respect to everything from confidence and sense of self-worth, to economic mobility and education -- this oppression is accomplished through words, images, laws, policy, violent force, etc.
