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It may be true that saffron is no sleeping potion, but an unduly large proportion of rascasse in the quick stew might have the same effect as a weak dose of the related stonefish poison.
In a similar behavioral paradigm, a weak dose of SL 650155, another 5-HTR4 pagonistagonimprovedroved memorization [5].
It demonstrates a very weak dose relationship, so dose reduction is often ineffective.
The review concluded that it was difficult to determine if this lack of improvement was due to small sample sizes, short intervention periods, weak dose effects, or ineffective interventions.
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Since enhanced solubility of recombinant proteins was reported at low temperatures and weak doses of inductor (Carrió and Villaverde 2002; Martínez-Alonso et al. 2009), both parameters were investigated in this work, but no improvement in soluble hydantoinase expression was observed (data not shown).
Transfection of wild-type RSPO1 cDNA resulted in weak dose-dependent activation of a β-catenin responsive TOPFLASH reporter (1.8 fold maximum), whereas co-transfection of CTNNB1 (encoding β-catenin) with RSPO1 resulted in dose-dependent synergistic augmentation of this reporter (approximately 10 fold).
For ara-C a weak dose-response relationship was observed.
Both Caov-3 and PA-1 cells showed a weak dose-dependent lysis with NHS and AF in the assay.
There were only weak dose-response relationships between blood levels of PCBs with cellular immune parameters, and of HCHs and HCB with humoral immune parameters.
There was a weak dose-response relationship, but the association was particularly apparent in the highest fifth of dietary intake (>23 μg day−1).
The dichloromethane extract gave a similar result except for a weak dose-dependent concentration against the SK-MEL-28 and Hep-G2 cells.
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