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These residues may all represent weak code, if they are used for base recognition.
On the other hand, when a weak code rate is applied, the channel is in an interference-limited regime and the benefits of mitigation techniques become more relevant.
The weak code starts losing diversity order earliest at SNR of 5 dB, while the moderate code's diversity order degrades at 10 dB.
Three codes with different error correction capabilities are presented: the weak code [5 7 5] with small minimum distance f=7, the moderate code [25 33 37] with f=12, and the strong code [133 165 171] with f=15.
Lys34 was regarded as a "weak" code for base G, although H-bond is found between the side group and the O6 atom of G. On the other hand, no H-bond is seen between Arg34 and base G.
Similar(54)
Therefore, when it comes to TALEN design, the codes for A and T may represent the weak codes.
However, it is also consistent with sequences that simply have weak coding propensity.
Our goal is to evaluate explanations for why these sequences, as a group, would show such a distribution of weak coding propensities.
Under the Z-curve model, a weak coding propensity corresponds to a Z-curve score that is intermediate between the CDS-like and 3'UTR-like distributions.
A third model, that the novel extensions as a group show a weak coding propensity by chance, is rejected by the Mann-Whitney U test, which demonstrates that the distribution of Z-curve scores is sufficiently different from that of distal 3' UTRs not to occur by chance (p = 1.02 × 10-23, Mann-Whitney U test, distal 3' UTR vs novel extensions).
Using a weaker code results in significant reduction in the ECC overhead.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com