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Exact(4)

We introduce a new problem which arises in the course of our project to design virus variants to serve as potential vaccines: we wish to modify virus-length genomes to introduce large numbers of unique restriction enzyme recognition sites while preserving wild-type function by substitution of synonymous codons.

Consider the cell as a computer that performs some useful task that we wish to modify.

The method of selecting these interventions is based on developing an understanding of the first deviations caused by the damage: in a regulatory chain A - > B - > C wherein node A is damaged, we wish to modify the regulatory relationships such that node B is not deregulated as an effect of the damage.

We wish to modify the node update rules to restore a specific attractor of the original network, given that the damage may not be directly reversed (e.g., in the example of Figure  1, given that node C will remain fixed in the OFF state).

Similar(56)

This issue, although important, remains to be explored for the actions of 4-CMTB and related allosteric ligands at FFA2, and thus, we wished to modify the orthosteric binding pocket of FFA2.

We now wish to modify the Φ function to consider code variants with fewer than 20 amino acids that may have existed prior to the standard code.

Similarly, he might wish to modify his view that it was Saddam Hussein's alleged connection with Al Qaeda that moved America to attack Iraq.

In music, scores from centuries past have preserved classic works, which modern composers may wish to modify, rearrange, or parody without loss of the originals.

When they do so, the tags (which are glued to their shells) talk to the nearest convenient satellite.Dr Read told the meeting that the tracking data he collects are now available online, to allow fishermen to follow the movements of turtles and, if they wish, to modify the deployment of their nets accordingly.

If Congress concludes the 2005 changes did not accomplish what they intended, "it would prudent to consider whether they wish to modify the code," he said.

Alternatively, readers may wish to modify the software to analyze other microarray annotation files.

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