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By searching the OMIM database (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi db = OMIM), we found that some human orthologs of the RP genes we targeted in zebrafish are located in chromosomal regions associated with diseases.
Further variants may lie outside the region we targeted, in more distant chromatin-regulating domains.
The two gene products we targeted in the tick synganglia were endogenous β-Actin and Na+-K+-ATPases mRNA.
The portion of the stem that we targeted in this analysis is also the part of the tree where petioles are actively developing and growing.
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It is especially the case in highly connected networks which we target in this paper.
Therefore, RSS is most valuable in high-density sensor networks which we target in this paper.
What can we target in this seemingly insurmountable list?
To evaluate AURKA as a therapeutic target in melanoma, we targeted AURK in human melanoma tumour implants growing in mice using an AURK inhibitor currently in clinical trials for solid tumours.
Here we used targeted in vivo analysis of cysteine cathepsins with ProSense 680.
In total we targeted about 2,500 in-school and 1,000 out-of-school adolescents.
"We targeted being in it, and we have fulfilled our target.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com