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We recently generated a mouse with a knock-down in FKRP in the muscle but not the central nervous system (FKRPMD).
We recently generated a novel chimeric form of the 4-1BBL costimolecule molengineeredneered with core streptavidin (SA-4-1BBL) andemonstrateded its safe and pleiotropic effects on various cells of the immune system.
We recently generated knock-in mice to visualize SPIG1-expressing cells with green fluorescent protein (GFP) [31].
We recently generated the Tg(osx:egfp b1212 line, labeling osteoblasts, in our laboratory by BAC-mediated transgenesis.
To address if PTPN3 functions as a physiological negative-regulator of TCR signal transduction, we recently generated PTPN3-deficient mice [28].
We recently generated a mouse line harboring a conditional Myog allele (Myogflox) and a Cre-ER transgene that allows us to investigate the role of myogenin in the adult mouse [8].
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In addition, to clarify the physiological function of Synoviolin in adult, we recently generate synoviolin conditional knockout mice using tamoxifen inducible Cre transgenic mice under CAG promoter.
We have recently generated an induction protocol specific for the generation of dopaminergic progenitor cells from human MSCs (11).
To understand the role of autophagy in age-related NMJ alterations, we used the inducible muscle-specific Atg7 knockout mice that we have recently generated (Masiero et al., 2009).
To address the in vivo functions of miR-142, we utilized a novel reporter and a loss-of-function mouse allele that we have recently generated.
For example, we have recently generated a probabilistic functional gene network for rice, called RiceNet (Lee et al., 2011; Lee et al., 2015).
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