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Planck [1909] argues that while we once defined heat according to sensations, the study of heat has gone beyond this, now being under the purview of electrodynamics and kinetic theory; similarly, tones and color are now understood as frequencies or wavelengths.
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We have once defined a strategy to merge orthologous groups based on profile-profile hits and complementarity of phylogenetic distribution (Dutilh et al, Signature Genes as a Phylogenomic Tool, Mol. Biol. Evol. 2008) and similar implementations of this idea may have been published.
Instead, the kinds of activities we might have once defined as "lame" (like, say, staying in to read a really great book) tend to bring us a lot more pleasure as we age.
If we're the generation that once defined ourselves as wanting to make the world a better place, now is our opportunity to do so -- and we've got another 30 years to do it.
We have let go of that line as we have let go of so much that once defined us.
Having forgotten the ideals that once defined our nation, what do we celebrate this Fourth of July?
Someone once defined leadership as telling us not what we want to hear but what we need to hear.
Values of goodness, which once defined our great nation, were now being defined by powers, we were told, were more wise than ourselves.
Politics was once defined as "show business for ugly people".
Spain had lacked the assuredness that had once defined them.
The walls that once defined offices are gone.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com