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We observed directly that the channel opens via the helix-tilt model and the open pore reaches 2.8 nm in diameter.
It is therefore possible that the caudate region we observed directly reflects this anatomical reciprocity between cortex and striatal hierarchical levels.
We observed directly and reliably for the first time, that both TM1 and TM2 swing away from the pore, supporting the helix-tilt model.
These results, by demonstrating that duration categorization in this task was dependent on a normally functioning striatum, suggest that the neural signals we observed directly supported duration judgments.
The list above shows examples of self-management tasks we observed directly, which correspond broadly to Corbin and Strauss's categories of 'illness work', 'identity work' and 'everyday life work' [ 29].
Using fs-TRLS, we observed directly the ultrafast DET reactions of XdUs with epre−, leading to the formation of the reactive radical (dU), but they are far less efficient than that of cisplatin, due to the lack of the NH3 groups as the effective electron-transfer promoter (Lu and Madey, 1999, Lu, 2010b), and thus have not sufficient radiosensitizing efficacies.
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Although integrating gravity into the model remains a fundamental challenge, the SM provides a beautiful explanation, from first principles, of much of Nature that we observe directly.
In this interpretation, the hierarchical structure is the source of autocorrelation or cross-correlation of spike trains, which we observe directly (Fig. 5) or indirectly (Fig. 3, Fig. 6).
Importantly, since CTCF binding information is encoded in high specificity cis elements, the intra-domain insulator dynamics we observe directly link local sequence evolution with chromosomal architectures.
We have observed directly that the floc at this location is washed downstream during rain events; the implication is that any arsenic associated with this material would also be transported.
Here, we have observed directly how the RNA travels to the posterior by tracking the movements of osk mRNA particles at high temporal resolution in living oocytes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com