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Although we observed broadly accelerated mRNA degradation at the switch (Additional file 1: Figure S6A), we noted this degradation to be relatively slower or faster for specific genes and functional classes and to often occur in concert with our previously described gene expression profiles.
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However, we observe broadly similar patterns between the two curves and therefore compare the trends between warm and cold phases.
That we observe broadly equivalent shifts of the G and 2D peaks where the graphene sits on the waveguide here indicates that the dominant cause of the shift is unlikely to be strain.
We used a standard approach to investigate heat effects in the three European cities and observed broadly consistent patterns in different sub-groups.
Time-of-day cycling has been observed broadly in mammalian brain for the major endocannabinoids anandamide and 2-arachidonoyl-glycerol (2-AG) [53].
RAD51 expression was observed broadly and was not associated with PTEN status in the 16 cell lines.
Whether this applies to intraspecific comparisons with much smaller evolutionary distances is not known, but we observed a broadly similar pattern of sense and antisense diversity in our MTBC lineage comparison, which may reflect the reduced purifying selection and increased genetic drift within MTBC (Hershberg et al. 2008).
So while the patterns we observe are broadly consistent with an effect of plant size on rates of mutation rates, the match to the observations is not exact, and there may be other factors at play.
The list above shows examples of self-management tasks we observed directly, which correspond broadly to Corbin and Strauss's categories of 'illness work', 'identity work' and 'everyday life work' [ 29].
More broadly, we observed similar shifts in gene expression between the miR-1-1 and miR-1-2 knockout mice (see number 2 below, Figure 2 figure supplement 2), some of which may represent direct targets.
Using both the Infinium and Agilent data, we observed that the distribution of broadly hypomethylated regions was very similar for both CVS and MBC genomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com