We initially focused on the inductive (Ras) signaling pathway, which is needed to initiate vulva development at the early L3 stage (Sternberg, 2005).
Thus, we initially focused on the growth and nutrient requirements for T. roseum.
We initially focused on studying TCR mobility on unstimulated T cells.
For this, we initially focused on the generation of progenitor cells along the dorsoventral axis at E10.5.
We initially focused on the WB-F344 cell line, the liver cell line from which many of the other cell lines studied were derived.
However, this cannot be conducted computationally; hence, we initially focused on the dimerization mechanism of hTLR10 with hTLR2 and 1 using protein-protein docking.
Dopaminergic neuron loss in the SNc is the prominent neuropathological entity in PD so we initially focused on the SN data sets for their convergence and reproducibility.
We initially focused on phosphorylation of Shs1 by Pho85 because active Pho85-Pcl1 canplexes can be readily purified after expression in bacteria [39].
Regarding the haplogroups examined, we initially focused on R-M269 which represents the individual haplogroup most shared not only in Sardinia and Anatolia, but also in Europe as a whole.
Since biologically effective changes in miRNA suppression of respective mRNA targets appears to have some minimal threshold, we initially focused on the top 50 miRNAs by read abundance at these three time-points (Figure 1A-B, Table S1).
To analyze how HIV-1 CTL escape mutations alter binding properties of peptide/MHC class I complexes to MHC class I receptors expressed on myelomonocytic cells, we initially focused on the immunodominant B8-FL8 epitope.
