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Finally, we inhibited notch ICD generation by chemical inhibition of γ-secretases using DAPT.
Finally, we inhibited adipogenesis and rescued osteogenesis of osteoporotic BMSCs by modulating those epigenetic modifications.
We inhibited cyclooxygenase type 1 and type 2 activities with selective inhibitors.
Firstly, we inhibited Erk 1 expression via siRNA targeted knockdown.
We inhibited JIP activity by applying SP600125 (50 µM).
To test this hypothesis we inhibited autophagosomal-lysosomal fusion using bafilomycin A1 (BafA) [74], [75].
When we inhibited RA signaling at gastrulation stage, HoxB4 was shifted posteriorly in chick endoderm.
We inhibited AR activity with the non-steroidal anti-androgen bicalutamide (Casodex) (Figure 2D).
Next, we inhibited the mTOR pathway in K and E cells.
To this end, we inhibited Wg activity in a two-cell wide stripe at the boundary.
To confirm the importance of fibronectin for the mechanical response we inhibited cell-fibronectin interactions with RGD inhibitory peptides.
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