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We have previously generated an ezh2+/ul2 mutant line using the TALEN technology26.
We have previously generated human pluripotent stem cell (hPSC -derived tissue-engineered small intestine (TESI) from hPSC -derivednal organoids (HIOs).
We have previously generated epidermal growth factor expressing Lactococcus lactis (EGF-LL) using bioengineering approach, and shown that feeding newly-weaned piglets EGF-LL improves digestive function.
We have previously generated epidermal factor expressing Lactococcus lactis (EGF-LL) using a bioengineering approach, and shown that EGF-LL fermentation supernatant enhanced newly weaned pigs growth.
As antibody fragment engineering has emerged as an economic alternative to mAb drugs via bacterial production, we have previously generated FM318, a recombinant Fab adopted from cetuximab.
By expressing human occludin and CD81 in an outbred ICR strain (C/OTg), we have previously generated an immune-competent humanized mouse permissive for HCV persistent infection19, and have successfully applied to a number of studies19,20,21,22,23.
We have previously generated human IgG1 antibodies that were engineered for reduced binding to the classical Fcγ receptors (FcγRI III) and C1q, thereby eliminating their destructive effector functions (constant region G1Δnab).
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These new data were analysed together with data we had previously generated from seven other sites, to allow comparisons among sites separated by up to 1800 km in this large contiguous region.
In our effort to develop variant-specific antibodies against HHV-6 immediate-early (IE) proteins, we had previously generated P6H8, a monoclonal antibody (mAb) reacting specifically with the immediate-early 2 (IE2) proteins from HHV-6A.
We had previously generated a transgene, Pglr-1::rfp::rab-5(GDP), which contains a mutated form of the rab-5 cDNA that can suppress the clathrin-dependent endocytosis of GLR-1 [56].
In order to adjust for multiple SNP testing, each prj is then transformed into a corresponding adjusted p-value, πrj, using the permuted replicates of the reconstruction table we had previously generated in the analysis of microsatellites.
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