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We demonstrated directly the energetic decoupling of PBsomes in vivo in response to the bleaching laser.
By comparing unilateral vs bilateral stimulation of SF1+ neurons in the same animal, we demonstrated directly that activation of a larger number of SF1+ neurons was required to evoke an activity burst than to evoke freezing.
In the present study, we demonstrated directly that when mitochondria are incubated under conditions that support rates of oxidative phosphorylation similar to those in situ, both the amount and the reduction state of cytochrome c do influence mitochondrial H2O2 production and that loss of cytochrome c from mitochondria during ischaemia can explain the observed increase in H2O2 production.
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Another important feature of elongation is that it is independent of size, as we demonstrate directly with empirical data of sea ice.
In particular, we demonstrate directly that disk/bulge systems can be built and rebuilt by the smooth accretion of gas onto the remnant of a major merger and that the present-day remnants of late dissipative mergers between disks are spheroidal stellar systems with structure resembling that of field ellipticals.
We demonstrate directly that some spontaneous DSBs occur outside of S phase.
We demonstrate directly in primary aortic root VSMCs that βarr2 modulates AT1aR-mediated MMP-2 and -9 expression.
Third, we demonstrate directly that primate-specific deaminase APOBEC3A caused GamGFP foci, and thus DSBs in human cells, indicating that DSBs result from DNA cytosine deamination.
Using the T2G mutant of N-TIMP-1, we demonstrate directly that inhibition of apoptosis of human neurons by TIMP-1 is in fact mediated independently of its effects on MMP activity.
In this study, we demonstrate directly that hypoxia leads to a significant increase in lactate efflux detected at the ventral surface of the brainstem, whereas our previous study reported profound hypoxia-induced release of ATP in the medulla oblongata an effect observed in anesthetized and artificially ventilated rats and in acute brainstem slices in vitro.
However, we have demonstrated directly that the eigenshapes we found are quite robust to image quality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com