We are currently applying the process in lung cancer studies where we target novel proteoforms of missing gene coded proteins.
Front cover: This image summarises some of the diversity of animal life, and encompasses organisms we have worked on in our group, including the threatened fish species that we are currently applying genomics to, to estimate evolutionary potential.
We are currently applying bounded set reconciliation in related domains, as any set reconciation can be made more robust if the complexity of the operation is bounded.
By confirming the major role of the microbiota in bowel-related disorders, which are especially associated with a disruption of homeostasis, we are currently applying high throughput functional metagenomic screens in order to identify signal molecules and mechanisms of bacteria-host cross-talk.
In another Beckley Foundation study located in Europe, we are currently applying for approvals to study the effect of LSD on cerebral circulation and brain activity, This study will compliment both the research at Berkeley, and the psilocybin research at Imperial.
We are currently applying the technology developed here to analyse monoclonal antibody binding to microarrays containing selected mutants of GAD65 (Buckle et al. in preparation).
Although the method applied would not be suitable to analyse the physiologic state of the cells, we are currently applying the lambda scan function of CLSM to analyse the physiological state of the photosynthetic pigments.
For example, we are currently applying it to the p53 pathway which regulates the cell cycle and is found to be de-regulated in 50% of human cancers [76].
We are currently applying the barcode approach to interrogation of cell size phenotypes in the context of different nutrient sources, ploidy conditions, genetic backgrounds and in the presence of various chemical reagents as well as 'perturbagens' to systematically decipher the global network that coordinates cell growth and division.
