"And by that route, we know it can displace oxygen, which creates an asphyxiation hazard, resulting in headaches and nausea and death at much higher concentrations.
As our proposed mechanism of Rpa displacement predicts, we find that Dna2 can displace Rpa from a 5' but not a 3' end, explaining how Rpa dictates the proper end polarity of the nuclease activity of Dna2.
Interestingly, RPA and NuA4 affect each other binding during DNA end resection and we show that NuA4 can displace RPA from single-strand DNA in vitro in an acetyl-CoA-dependent manner.
It has been suggested that in Gram-positive organisms the roles of both UvrD and Rep are combined in a single essential helicase, PcrA [32], and we have shown that PcrA can displace both UvrC and the damage-containing oligonucleotide from a post-incision NER complex.
We need a solution for energy production that can displace the rapid growth of coal use today.
Finally, we sought direct evidence that the HIC 3'UTR can displace 7SK RNA from P-TEFb complexes.
The displacement hypothesis suggests that SB can displace time that could otherwise have been used for PA [ 47].
Previously, we have shown that a peptide that binds the DRS can displace Ets from ERK2 [11].
To further examine the qualities of the heme interactions of these mutants, we added exogenous imidazole (a structural mimic of histidine that can displace transient heme ligands to each purified HCCS cocomplex and obtained UV vis absorption spectra.
We speculate that when present at a relatively high concentration, phosphorylated HspB6 can displace certain enzymes (protein kinases, phosphatases, etc).
