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For each individual, we calculate whether they were exposed to either intervention for the entire period from 0 36 months of age.
We therefore first determine whether the newly synthesized positive-sense strand is packaged; then, for unpackaged genomes, we calculate whether they remain in the replication complex.
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For each resampled pair we calculated whether the Euclidean distance of the resampled pair was greater than that of the original pair, i.e., if d ( j ′, k ′ ) > d ( j, k ).
We calculated whether the observed optima seemed to change between sessions and by how much.
On the basis of these assumptions, we calculated whether patients at any time had tablets available or not.
Following pilot tests using an anemometer (Tacktick) and software (Pi Toolbox, Cosworth Electronics), we calculated whether various wind directions and wind speeds could be accurately simulated.
To examine these data more closely, we calculated whether the Ka/Ks Ψ - ortho values are significantly less than would be expected for mutation without coding-sequence selection pressures (using the simulational analysis described in the Methods section).
Specifically, we calculated whether the direct superclasses on each side of the paired correspondences were also matched in the alignments—superclass matches were considered evidence of similar structure (i.e. relations made in similar ways/directions).
Before any analysis, we calculated whether the available number of patients (225 patients in the diagnosed group and 117 in the undiagnosed group) would allow for identification of clinically significant differences in outcome between groups (diagnosed vs. undiagnosed).
Based on the finding that a combination of IL-6 concentration and CRB-65 score had the best discriminatory power, we calculated whether the addition of IL-6 concentration to CRB-65 score improved the classification of individual patients by calculating the NRI.
We calculated whether the participant had tablets available on the day that we sent the questionnaire (the number of tablets on the last redeemed prescription before the questionnaire was sent ≥ the number of days to the questionnaire was sent) and defined the participant as 'receiving treatment' if tablets were available.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com