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As this imposes the assumption that the trend divergence is linear, we additionally check alternative more flexible specifications of such trends by the use of quadratic and cubic polynomials, i.e., begin{array}rcl@ Psi_{mathrm{treatment,group,t}}=T_{t}*mathrm{treatment,group}_{i}*psi_{1}+T_{t}^{2}*mathrm{treatment,group}_{i}*psi_{2} end{array}.

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We additionally checked the influence using a case where the linear expansion coefficient had an uncertainty of 5.0 × 10−7/°C, where the temperature difference was 10 °C and where the maximum relative height from benchmark BM34 was approximately 350 m.

Whenever weighted regression was used we additionally checked that the non-parametric Spearman rank test yielded the same conclusion.

We additionally checked the probability of reaching the G1 stationary state, starting only from those initial conditions, when "Start" is active on the first time step.

We additionally checked these Transcript Active Regions (TARs) for open reading frames.

We additionally checked that the assumption of 1 1 binding to DNA and ocr was correct for the GFP-MTase as previously established for the normal MTase.

Thus, we additionally checked our specific gene sets of interest ("regulated", "targets", "regulated targets") for the presence of an expression bias in general (Author response image 5).

As OLP did not pass the Shapiro-Wilk test, we additionally checked the q-q plot, which did not show marked deviation from linearity.

Instead of relying on a single algorithm for deleterious mutation prediction (SIFT), we additionally checked the consistency of our result using an integrative database dbNSFP v.2.5 (Liu et al. 2013).

We additionally checked the effectiveness of this dosage regimen in pilot experiments conducted in three dogs receiving an intravenous bolus of 0.25, 0.50 and 1 mg/kg-1 (data not shown).

Since FFM has previously been shown to vary with age group [Table 4, Model 11; [ 42]], we additionally checked for DRD4 by age group and DRD4 by residence by age group interactions, but these were not evident (not shown).

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