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Photodynamic therapy is an expensive treatment that entails substantial risk and inconvenience.
Both moves typically entail substantial new R&D and marketing capabilities and are fraught with risks.
The analysts added that the potential deal would likely entail "substantial" cost savings over three years.
The high incidence of injury in rugby union, influences team performance and entails substantial treatment costs.
Providers can offer such a product, but going beyond the standard plain-vanilla product is likely to entail substantial risks.
Viral and cellular proteins are involved in mediating this 'nuclear egress' which entails substantial remodeling of the nuclear architecture.
Due to low pH soils which are common in this region, N removal by denitrification may entail substantial N2O emissions.
Also, he knew that a replacement engine would entail substantial redesign work to the aircraft, and it'd probably send the price over the $1 million mark.
And moving back into a world of ash and rubble would entail substantial health risks, especially for someone with breathing issues, as Mr. Cayer well knows.
First, production entails substantial fixed costs; and second, preferences differ across groups of consumers.
Finally, the process of optimization is not necessarily efficient and may entail substantial trial and error.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com