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Use of such multifactorial models, including interactions, may pave the way to prediction of diabetic nephropathy and other complex genetic diseases in other populations.
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Predictions of 3 to 4 percent growth in January have given way to predictions this time of half that, or less.
With plenty of oil still left in familiar locations, forecasts that the world's reserves are drying out have given way to predictions that more oil can be found than ever before.
This has given way to predictions that vaccines, drugs and other interventions will eventually be tailored according to an individual's genetic make-up [ 5, 6].
The group studied the contribution of smoking status, measured in multiple ways, to prediction of COPD.
The apocalyptic view also shifts the focus of future expectations from predictions of punishment lest people change their ways to predictions of events that must occur, regardless of human actions.
The major difference between the perceptual and motor systems is that in the former the only way to change prediction errors is to change predictions; however, in the latter, predictions of sensory input can be 'fulfilled' by movement; in other words, prediction errors can also be altered by changing the signals that are predicted.
However, there is another way to minimise prediction errors; namely, by re-sampling sensory inputs so that they conform to predictions; in other words, changing sensory inputs by changing the world through action.
The advance clearly points the way to a prediction made in 1959 by the physicist Richard Feynman that "there's plenty of room at the bottom," referring to the possibility of building atomic-scale systems.
Leave-one-out cross-validation is an effective and objective way to evaluate prediction performance [14], [15], [16].
The possibility to derive this information directly from 3D structure opens the way to the prediction of important residues in proteins, while the confirmation of the minimization of APSP for folding allows for the establishment of a potentially useful proxy for kinetic optimality in the validation of sequence-structure predictions.
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