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This assay evaluates a novel wavelength modulation SPR biosensor for the detection of tetanus toxin.
The second harmonic detection of wavelength modulation spectroscopy (2f-WMS) is employed.
The results illustrate how wavelength modulation SPR biosensor can be used to detect biomolecular interactions.
Wavelength modulation spectroscopy with second-harmonic detection (WMS-2f) was used to measure CO2 near 2752 nm.
The sensors operate using multi-pass spectroscopy with wavelength modulation method (MUPASS-WMS) and cavity enhanced spectroscopy (CEAS).
Wavelength modulation spectroscopy and a 2nd harmonic detection technique were used to reduce the sensor background noise.
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However a joint mileage and wavelength domain analysis of the monitoring data can provide crucial information about the simultaneous amplitude and wavelength modulations of the corrugation modes.
Although we do not have a specific example of long wavelength modulations in mind, we conjecture that these might be associated with inter-area cortical connections.
The long-wavelength modulation increases the fluorescence without generating any additional background in the higher-energy fluorescence detection channel.
An acousto-optic tunable filter-surface plasmon resonance (AOTF-SPR) immunosensor based on wavelength-modulation was applied to detect fibronectin by direct, sandwich and colloidal Au-enhanced immunoassay.
The design of the wavelength-modulation AOTF-SPR immunosensor is based on fixing the incident angle of light and measuring the reflected intensity of light in the wavelength range spanning 440 790 nm.
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