Wounding Induces Calcium Waves in the Drosophila Embryonic Epithelium Movie showing immediate induction of a calcium wave after wounding of an embryo expressing epithelial mCherry-moesin (red) and GCaMP3 (green).
Prior to wounding, GCaMP3 fluorescence, and hence cytosolic calcium levels, did not alter in the epithelial cells; however, laser wounding resulted in a rapid calcium flash extending outward from the point of wounding as a wave to an average maximum distance of 39 ± 4.8 μm from the wound margin (SD, n = 6 movies) at a speed of 6.9 ± 2.5 μm/s (SD, n = 7 movies) across multiple cells.
We have also found a consistent link between wound-healing rate and the intensity and speed of the calcium wave after wounding.
Plants were cut horizontally through the mid-stem and left at room temperature to release the first wave of wounding-related oxidative burst.
Extra nurses and surgeons were called in to prepare for the waves of the wounded.
Other British commandos cheered and waved, Mr. Millin recalled, though he said he felt bad as he marched among ranks of wounded soldiers needing medical help.
A masterpiece of wounded innocence.
Quantification of the number of hemocytes at the wound site over time in a control situation suggests that within the first 30 minutes after wounding, a first wave of rapidly responding hemocytes reaches the wound site (Fig. 3B).
Military medicine, under the pressure of successive waves of the severely wounded, has created breakthroughs in prosthetics, surgical techniques and regenerative medicine, among others.
Working in a field hospital in Kuwait, he experienced the first waves of the severely wounded as the Iraq war ignited into a raging and bloody insurgency.
In particular, failure of the wave of myofibroblast apoptosis during wound healing combined with an autocrine feed-forward loop of TGF β production leads to the development and persistence of large numbers of myofibroblasts, a hallmark of fibrotic disorders.
