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All animals were then given 5 days of washout (experimental days 8 12).
However, after 5 days of washout (experimental day 13), animals treated with 2.5 mg/kg (i.e., experimental day 13) MDMA showed a significant increase in locomotor activity across all four locomotor indices when compared with experimental day 2.
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After 25 days of washout (on experimental day 38), animals re-challenged with 5.0 mg/kg exhibited sensitization across the HA, VA and NOS indices.
These drugs had high potency, very slow kinetics, apparent irreversibility (no recovery within the 200 s of washout within this experimental environment) and no use-dependence.
Rather it can be expected that dissolution and re-precipitation are dominant processes in the high-tempered experiments compared to washout effects of pre-experimental weathering at low temperatures.
Currently, expiratory washout is still limited to experimental use.
Animals were fed with the AIN93M diet during a 1-week washout period and during the experimental period.
The total study duration for each subject, including screening, experimental sessions and washout, and the final study visit, was at least 6 8 weeks.
IL-6 has been detected as an abundant cytokine in washouts of inflamed joints under many experimental model conditions.
Once a week, throughout the entire experimental period (basal, treatment and washout), samples were collected from the reactors for analysis SCFA and ammonium.
At weekly intervals, throughout the entire experimental period, (basal, treatment and washout), 5 mL samples were collected from the reactors for microbiological examinations.
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