Our findings that modulating PRAS40 was without consequences for mTORC2-dependent effects on cell cycle and cell size regulation (Fig. 5C, E and F), additionally support the here suggested model of mTORC2 controlling both, cell cycle progression and cell size, by regulating TSC2.
It said: "It will be some time before the implications of the tighter liquidity and credit conditions now set to prevail well into 2009 become clear, but it is logical that these will not be without consequence for SIG's markets and customers".
In all states, lying is "protected activity" under litigation privilege, and is without consequence for lawyers.
"It is hard to imagine that this attack will be without consequence for the people who enjoy free healthcare at the hospital in Gao," Mbaoh Nana said, noting that the Red Cross has provided the facility with "logistical and human resources since 2012".
Of the two cases of shoulder dystocia in the placebo group, one occurred with a macrosomia; however, all the cases were without consequence for the neonates.
Because the performance of one freeze-thaw cycle is without consequence for assessed CT-proET-1 concentrations, and the study samples underwent one freeze-thaw cycle, no influence of frozen storage on assessed concentration is to be expected.
The Egyptian revolution has not been without consequences for her.
"Because it won't be without consequences for any of us in Europe".
Neither this fact nor West German anticommunism in general were without consequences for the internal development of the SED dictatorship.
Although this may be without consequences for the general classification of a substance as an EDC that disrupts metabolic end points of hormonal regulation, it may complicate clarifying its mechanism of action with the aim to design other chemicals as adequate substitutes without endocrine-disrupting properties.
Uniparental disomy (UPD) is the abnormal situation in which both members of a chromosome pair are inherited from one parent, and the other parent's chromosome for that pair is missing. 1 Uniparental disomy for some chromosomes is without consequence, but for a few chromosomes can result in abnormality in the affected individual through parent-of-origin differences in gene expression.
