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The clinical course during the first 48 h after hospital admission was usually severe, with 63.5% of patients requiring mechanical ventilation.
Considering that the response rate with cytokines was very low (5%200%), the median OS not exceeding one year and then on other hand the toxicity was usually severe, in particular when elderly patients were treated, cytokines were not usually used in elderly patients.
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Radiotherapy may be of some benefit, but local sequelae are usually severe, and wound healing after combined surgery and radiotherapy is severely impaired [1].
Mental retardation is usually severe.
The headache is usually severe, often occurring on one side of the head and pulsating in nature.
When this coordination is lost, the result is usually severe constipation.
Penalties for those who identify rape victims, for example, are usually severe.
When a highly drafted quarterback struggles so consistently and fails to develop, there are usually severe ramifications.
This is why, in marriages of one man and one woman, there are usually severe and public consequences for spouses who are discovered to be unfaithful.
More than half of the migraineurs (54.2%) reported that their headache attacks were usually severe.
Symptoms are usually severe but last only for a couple of minutes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com