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The overall response rate for all CMHWs was therefore 86.77%.

The total number of enrolled patients was therefore 1383 (81.9%).

The response rate for SCLC cerebral metastases treated with chemotherapy was therefore 10/19 (53%).

The remaining number of fully screened children was therefore 1,957 833%).

The water sample was therefore 2,000 times concentrated (20 L water giving 10 mL methanol solution).

The total required sample size for the whole study was therefore 6500.

The probability of PD-free survival over three months was therefore 51/59 = 0.86.

The average time taken for a single SNP analysis was therefore ~0.139 s.

The required sample size was determined to be 1,844 children for each age group; the total required was therefore 7,376.

Total trial length was therefore 2,725 msec, with trial onset jittered relative to the repetition time (TR) of 2,000 msec.

Our practice sample size was therefore 7957 (out of 8305 practices in England with Quality and Outcomes Framework (QOF) data).

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