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Derivatization was systematically optimized by employing a factorial experimental design.
The BHJ morphology was systematically optimized by additives, thermal annealing (TA) and solvent vapor annealing (SVA).
Secondly, Kinetics of degradation was systematically optimized by multi variable central composite design based on response surface method.
The BHJ morphology was systematically optimized by thermal annealing, solvent vapor annealing, and the use of solvent additives.
Then, BT pathway was systematically optimized with gene homolog screening strategy, mainly targeting three key steps from xylonic acid to BT catalyzed by d-xylonate dehydratase (XD), 2-keto acid decarboxylase (KDC) and aldehyde reductase (ALR).
The developed tandem biotransformation process for the directional biosynthesis of a designed compound 4- 2,3,5,6-tetramethylpyrazine-1 -4′-demethylepipodophyllotoxin (4- 2,3,5,6-tetramethylpyrazine-1 -4′-demethylepipodophyllotoxinimized.
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The effects of number of beds, PSA cycle configuration and various operating and design parameters on the separation quality and power requirements have been systematically optimized using recent advances on process optimization.
With CCD, these factors can be systematically optimized taken into account of their interaction effects.
The batch reaction conditions for the synthesis of l-Tle were systematically optimized.
The growth conditions were systematically optimized with the help of computational flow-field simulation.
With the introduction of the BYY learning algorithm, FCMAC-BYY has higher generalization ability because the fuzzy rule sets are systematically optimized by BYY.
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