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Thus the endogenous potential of procoagulant activators was sufficient to activate fibrinogen and to terminate bleeding.
In the same study, authors demonstrated that constitutive activation of Akt was sufficient to activate actin assembly and resulted in increased cell migration even in the presence of Ly294002.
In this study, a single gRNA targeting an enhancer region with dCas9-P300 core was sufficient to activate target gene expression, whereas other dCas9 activators required several gRNAs to achieve high levels of gene expression [ 106].
We observed that treatment with TRAIL alone and in combination with R-roscovitine was sufficient to activate caspase-8 as early as 8 h after treatment and this activation persisted until 24 h (Fig 5b; top and bottom panel).
Conversely, at the plot-scale, the sampled volume was sufficient to activate the macropore network.
For higher Ag contents (zone II) the energy supplied by thermal treatments was sufficient to activate the crystallization of Ti Ag intermetallic phases.
Their brainstems were prepared for fos protein immunohistochemistry at the level of the trigeminal nucleus caudalis [18] to determine if the stimulation was sufficient to activate the trigeminal neurons.
Fortunately a felt-tip pen was sufficient to activate the switch.
Similarly 125 µg/µl of the crude MF101 extract was sufficient to activate both ERα (Figure 1C) and ERβ (Figure 1D).
However, high FADD was sufficient to activate Caspase-8 and -10, with addition of death receptors only modestly further increasing reporter gene activity (Figures 3E, F).
In this study, IL-1β was sufficient to activate testicular endothelial signaling pathways promoting neutrophil recruitment, and causing germ cell-specific apoptosis [43].
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