Sentence examples for was substantially upregulated from inspiring English sources

PDGF-BB expression was substantially upregulated in hypoxic cardiomyocytes.

Although neither TGF-β2 nor TGF-β3 expression was affected by hypoxia, the TGF-β type I receptor was substantially upregulated within 6 h.

The mRNA transcript for TNFα was substantially upregulated in wildtype cells treated with each of the TLR2 ligands, or when LPS was included as a positive control.

7 cells and derived osteoclasts shows that, indeed the expression of PDGF-bb, VEGFc, LIF and IL-1ra was substantially upregulated during osteoclastogenesis (a 13, 36, 73 and 25 fold increase, respectively) whereas that of CCL9 and Twgs 1 was upregulated only 2 4 fold (Table 1).

By flow cytometry (Figure 8E), the baseline expression of phosphorylated 4E-BP1 and p70S6K1 proteins was higher in the CD4+CD25neg T cells than the CD4+CD25high cells, and after OKT3 and IL-2 stimulation, it was substantially upregulated only in the CD4+CD25neg cells.

ZK637.13 was substantially upregulated in daf-2 e1370) daf-2 e1370 dadultsdependent fashinn.

Certain MMPs that are expressed at very low levels in normal myocardium such as collagenase-3 (MMP-13) and the membrane-type MMPs (MT-MMPs) are substantially upregulated in CHF and likely contribute to the pathologic remodeling that occurs within the myocardium.

In our initial study of the effects of HIFs on gene activation, PTPRZ1 was identified as one of 10 genes that were substantially upregulated by HIF-2α but not by HIF-1α [11].

Since postmortem studies have shown that the Ilk-1→NFkB innate immunity pathway is substantially upregulated in the brains of AD patients, the demonstration that the Tl→NFkB signaling actively promotes the process of Αβ42 induced cell death and tissue degeneration in flies points to possible therapeutic targets and strategies.

We found that AhR is normally expressed at low levels in the prostatic epithelium basal cells (cytoplasmic and nuclear staining, Figure 6A) and is substantially upregulated in areas of proliferative inflammatory atrophy (PIA), considered a precursor lesion to cancer (Figure 6B).

Notably, TGFB2 and TGFBR2 were substantially upregulated only in the HRG.