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But it can get tricky, especially in higher stakes transactions such as employment, insurance and credit, where he said there was substantial concern regarding privacy, data quality and fairness.
There was substantial concern during the course development phase that students would not react at all positively to the course, given the fundamentally different nature of an interdisciplinary, quantitative course within a fairly traditional, single-disciplinary curriculum.
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There has been substantial concern that aspen has been declining in the western US, but trends of aspen persistence vary both geographically and temporally.
In the other countries there is substantial concern that the increased use of asbestos may result in an increase in the number of cases of MM for many decades.
Although there is substantial concern about negative attitudes to mental illness, little is known about the stigma associated with Generalised Anxiety Disorder (GAD) or its measurement.
Furthermore, there has been substantial concern in the literature about how stand-alone programs may drain government of scarce expertise (25, 26).
Along with the above barriers to implementing TRIPS flexibilities, there is substantial concern among public health advocates about the spread of so-called "TRIPS-plus" measures.
As-needed [ 103] and episodic high-dose [ 104] ICS have also been studied, but there is substantial concern about the risk of side-effects with their over-use, so regular low-dose ICS should be tried first.
In the United States, a revised drinking water standard for arsenic of 10 micrograms per liter (μg/L) is set to take effect in January 2006, but there is substantial concern that this level is still too high for public safety.
In addition, there are substantial concerns about political stability in Bahrain and Saudi Arabia's oil-rich eastern province, and potentially even in Kuwait and Jordan – all areas with substantial Shia or other restless populations.
"Much of the debate around that has been about the threats of Brexit to Scotland, of which there are substantial concerns, but also there's an opportunity here," Dugdale said.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com