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We observed the selective killing of the HLA-A3-positive melanoma cell line FM3, and this killing was specifically inhibited by cold target inhibition with the addition of T2-A3 cells pulsed with gp100614-622, whereas it was not affected by addition of T2-A3 cells pulsed with an irrelevant peptide (Fig. 3e).
p38 phosphorylation was specifically inhibited only by its specific inhibitor SB202190 (P < 0.05, vs IL), but not by Erk inhibitor PD98059 or JNK inhibitor SP600125.
These results demonstrate that fhMAb 27.B1 binding to the same 42 kDa band was specifically inhibited by the recombinant protein and this confirmed the specificity of this antibody to the GIPC1 antigen.
Binding to the lectins was specifically inhibited by a monosaccharide or a disaccharide that competes the binding to the same lectin, which confirmed the binding signal was specific.
Activation was specifically inhibited by PKI.
This selective gene transfer in MMP-rich cells was specifically inhibited by 1,10-phenanthroline, a broad-range MMP inhibitor.
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Downregulation of HDAC1 is specific to the I-groups and may indicate that repression of transcription is specifically inhibited.
MurA is specifically inhibited by phosphomycin [28], and the mechanism of inhibition is well understood [29].
The data demonstrate a mechanistic role for COX-2 in vascular channel formation, with significant inhibition of channel formation when COX-2 is specifically inhibited.
We demonstrate that specific recombinant MSP-134 469 MSP-134 469nding to red blood cells (RBCs) is specifragmentinhibindingy non-modified MSP-142–61, as well as by ito V52-L53, M51-V52 reduced amide surrogates and partial-d subloodutions in K48 and E49.
Staining of immunoblots of rat brain membrane fractions is specifically inhibited by preabsorption of the antibody with this peptide (manufacturer's specification).
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