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The expression of Noxa or Puma was slightly modulated by Len/VD3 in some cell lines, while that of Bik was markedly increased in all responsive cell lines.
Moreover, when comparing PBLs with CRC LS174T cells, we observed an undetectable basal level of TS protein unmodified by vorinostat, whereas the TS transcript was slightly modulated by the treatment (1.5-fold reduction after 24 h).
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Furthermore, phase deflections of stimulation artifacts are slightly modulated by each heartbeat and respiration.
We found that the Pc1 packets are slightly modulated as they propagate from high to low latitudes in the ionospheric duct.
In Fig. 7, we also noticed that the Pc1 packets are slightly modulated as they propagate from MGD to MSR through PTK (e.g., 1028 25 UT and 1029 40 UT).
Although this close-to-Mendelian pattern of genetic control is slightly modulated by the MHC-linked QTL (N.
IL1R1 and APOD levels are slightly modulated in BCAR1 cells, in agreement with the hybridisation data.
ZNT1, not spotted on the microarray, was also tested in kinetics with qRT-PCR and was found to be slightly modulated with a biphasic response; first down- then up-regulated (figure 2).
Other genes that were slightly modulated by L-cysteine deprivation included methionine adenosyltransferase (MAT) and phosphoglycerate dehydrogenase (PGDH), which were induced by >2 fold at early (3-6 h) and late (24-48 h) time points of L-cysteine deprivation, respectively.
indicates statistical significance (p ≤ 0.05) The results of the multiple regression analysis for catalase showed that serum levels were slightly modulated by the mtDNA haplogroup J, bordering on the statistical significance, so that carriers of this haplogroup have higher levels than non carriers (p = 0.057) (Table 4).
The Et-KuQ pKa defining the equilibrium between the protonated and deprotonated form is 5.6 in solution and this value can be slightly modulated by the protein environment, facilitating the acceptance of an hydrogen by the two oxygen molecules that are at an average distance of 6.7 Å from the oxydryl group of the DNA 5′end in the docked complex with the covalent enzyme DNA structure.
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