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Conversely, 83% of the individuals that downregulated IL-10 production (PPD stimulated IL-10 levels were lower than the unstimulated background) were TST responders, and this was significant using the Chi-square test for trend (p = 0.0485).
As indicators of heterogeneity of pooled effect sizes, we calculated I2, which indicates the heterogeneity in percentages, and we tested whether the level of heterogeneity was significant using the Q statistic.
We further investigated whether the non-coherent target set of synaptic transmission was significant using the non-target synaptic transmission genes as controls because on average, late-expressed synaptic transmission non-target genes have a higher fold-change from P7 to P60 than do other non-target genes.
This effect of lowering AUC was significant using all methods of AUC analysis.
Stratified analysis was conducted where an interaction was significant, using model 2.
The distribution of PUNLMP and high-grade tumours was significant using χ test (P=0.009).
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An additional 51 SNPs were significant using a more permissive significance threshold (false discovery rate (FDR) < 0.1).
These findings were found to be significant using a Cochran's test for related observations.
In an attempt to reduce the chance of a type I error, we have only presented results that were significant using both the Mann–Whitney and t-tests.
Skewness and GLNU were significant using WT method.
As Table 2 shows, all group differences were significant using this conservative criterion.
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