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Furthermore, the w ratios of the branches leading to the avian and mammalian lineages were larger than 1, indicating that the emergence of eutherian PL10 homologs was selected positively to acquire species-specific gene function and purifying selection acted on the DDX3X and PL10 homologs to preserve their crucial biological function and avoid their divergence.
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However, some were incorporated into their genomes and became functional, so were selected positively, presumably because they were advantageous to their host animals.
For identification of proteins being selected positively, dN/dS ratio was calculated in pairwise manner for the set of orthologous proteins which were further aligned using CLUSTAL W algorithm [ 48].
For risk assessment, the opposite information is very valuable as well because it would indicate regions where the crop allele is selected positively and should therefore be avoided as places for transgene insertion.
How many times has a mutation occurred that was then selected positively to reach high prevalence today once, twice, many times?
Only the sites which were common in all the four methods were selected as being positively selected (Total 7).
In many cases, information needs to be selected, prioritized and positively labeled to be put into action.
Microvascular colonies were selected and ECs were positively selected using Dynabeads CD31 (Invitrogen).
Within the G gene of HMPV-A, fourteen codons were positively selected, six were positively selected within HMPV-B1 and 17 sites were identified as under positive selection within HMPV-B2 (Table 3).
Our finding that heart enhancers tend to be positively selected is particularly intriguingly.
The evolution of PL10 homologs was positively selected.
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