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The changes were refined again in a 1938 revision.
"They were refined again and again to make sure that they were functional and not too throwaway," Ton says.
Note that in the proposed stop criterion of the concurrent TZ search algorithm, even when a PU was refined in the previous refinement iterations or when this PU already contains its best match position, whenever a better search position is determined, this PU partition must be refined again.
It is obvious that the 2N × 2N and N × 2N part-1 PUs must still be refined again, as the distances from their current best match points to their search centers are both greater than 0, whereas no changes are made for the case of the N × 2N part-0 PU.
After that, the B factors for the NO molecules were refined again.
Third, the rebuilt structure model is refined again with the same parameter settings as the last step of the conservative refinement, but with three different geometric restraint weights: the optimal weight from the conservative optimization phase, a slightly tighter restraint weight and a slightly looser restraint weight.
The process eventually was refined.
And the marketing was refined.
It was refined.
Chemotherapy was refined.
The final algorithm was refined a bit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com