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This salt bridge was recapitulated in simulations of the cTnI A164R variant.
Furthermore, HSCs activation due to increased hepatic oxidative stress observed after in vivo arsenic exposure was recapitulated in co-culture model of isolated HSCs and hepatocytes exposed to arsenic.
We designed and characterized a phage clone in which this domain exchange architecture was recapitulated as an antigen binding fragment dimer [(Fab 2]on the phage surface by protein engineering.
The unequal amplification of differently sized alleles was recapitulated in vitro (Figure 1C).
This effect was recapitulated in cell extracts by the application of the ROS hydrogen peroxide.
The class III phenotype of deregulated secretion of ExoU was recapitulated for these derivatives (no NTA, Fig. 5D).
This same phenotype was recapitulated in 4TO7 cells that had stably silenced Zeb2 expression (Figure 5D and 5E)).
The mRNA expression for IL-17A in glioma was recapitulated in an immunocompetent mouse model of malignant glioma.
The reported interaction between LIN28B and Let-7 was recapitulated by siRNA knockdown in ovarian cancer cell lines.
These experiments showed that the response to the pool was recapitulated by stimulation with either of two individual 15-mers (Fig. 1B).
Importantly, the suppressive phenotype of human Tregs expressing the TyrTCR was recapitulated in vivo using murine Tregs and antigen-specific Teff cells.
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