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That was the same problem the Paphitou rule encountered, as performance in the original single-center study was quite predictive, but when we attempted to validate it in a multicenter data set, the rule lost a significant amount of sensitivity and specificity.
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In addition, the positive predictive value was quite low, indicating that the results of the cuff-leak test should not be used to postpone the extubation but might be particularly useful to exclude significant laryngeal edema [ 4, 5, 7, 16].
However, our results of cluster analysis showed that while the optimal number of the clusters varied from two to three, their overall quality metrics were not definitive: average silhouette width, ASW was modest (ASW < 0.389) but the predictive strength was quite high (PS > 0.8 for Jensen-Shannon and Bray-Curtis metrics).
In our series, TVS's diagnostic performance in the investigation of borderline ovarian tumors was quite satisfactory (sensitivity 50%, specificity 92%, positive predictive value 11%, and negative predictive value 99%).
8 The education of the women is quite strongly predictive of the rate of entry into marriage, showing a U-shaped relationship.
And so McAuliffe's polling, predictive modeling and voter targeting was, quite likely, vastly superior to Cuccinelli's and to the public polling.
Perhaps as importantly, the negative predictive value of these assays was quite high.
It is, however, worth noting that the negative predictive value of PCT using such threshold values was quite low.
The negative predictive value (NPV) of a score < 5 was quite high (85.9%), which is very important as a screening instrument should have a high NPV.
"It was quite primitive," Hernandez said, "but for the dawn of the computer age, the predictive results seemed miraculous".
The single strand with maximum intensity was also quite predictive and would be important for RNA assays.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com