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Specifically, FnCas9 can only tolerate a mismatch on the 5′-end position distal to the PAM, whereas SpCas9 can tolerate the mismatch on six positions, one of which was proximal to the PAM and a high level (31%) of indels was induced on the mismatched target.
On the first of the four shift trials (where the newly positioned platform was proximal to the rat's starting position), female rats showed the previously found tendency to adopt a perceptual style escape directly in clear contrast to saline-treated males.
Surprisingly, we found HF2-BE2 could also deaminate C that was proximal to the gRNA-binding region.
Because the CORA was at the ankle joint and the supramalleolar corrective osteotomy was proximal to it, a translation of the distal tibia was performed with the application of a juxta-articular hinge (Fig. 3).
For the seven LMW-GS genes at Glu-D3, D3-1 was proximal to other six members.
On the other hand, the algorithm detected two potential 5'-ends for the atf1+ transcript: one was proximal to the atf1+ coding sequence (∼340bps) and the other was distal to it (∼1.4Kb) (Figure 3B).
Similar(33)
Interestingly, the NES of TFEB encompasses the S142 phosphorylation site and is proximal to S138 (Fig. 2a, b).
Thus, it is possible that changes in Adcyap1 expression are proximal to the cascade of events modulated by inositol depletion.
In addition, ribbons labeled with the fusion protein are proximal to afferent nerve endings.
The catalytic C85 residue in E2 (mutated in silico from Lys to Cys18) is proximal to C4520, which undergoes transthiolation with E2 Ub.
These residues are proximal to Hyp531, make contacts with pVHL, and are predicted to contribute to the stability of the pVHL-HIF-2α interface.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com