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It was predefined that dose escalation of everolimus will be stopped at 10 mg/day in case a MTD is not achieved.
Although it was predefined that comparative secondary efficacy analyses on OS and PFS (central RECIST) were to be carried out upon success of the noncomparative primary analysis, no order for sequencing secondary analyses was specified.
An interim analysis was scheduled at 60 patients; the stopping rule was based on the Haybittle-Peto boundary, i.e. it was predefined that the trial should be stopped early for a p < 0.001 between visits [ 9, 10].
In order to be able to correlate the baseline and on-treatment blood and tumour parameters with the biological effect of IL-2 with and without histamine, it was predefined that only patients receiving at least 80% of the scheduled drug dose within the first treatment course were assessable for the present analyses.
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Figure 3 shows a trapped membrane being transported along a circular path that was predefined using the control software for the spatial light modulator.
From the topic that was predefined as dangerous, the system will extract the object name and classify it as a dangerous object.
The Kappa value for inter-observer reproducibility between the two readers for the 38 cases was 0.51, which was lower than the limit of 0.6 that was predefined as acceptable.
Within the imagination of others, my existence was predefined.
where and are predefined threshold values that are used to determine the edge and flat and pattern edge regions.
For the optimisation, the settings that were predefined in the model files supplied by DegKin manager were generally not changed.
The VHDL-2008 versiof of the package defines array/scalar logic operations for std_ulogic and std_ulogic_vector values, mirroring those that are predefined for bit/bit_vector and boolean/boolean_vector.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com