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These descriptors were then grouped into 5,000 clusters with k-means algorithm [19] (the number of clusters/visual words was optimized between 500 and over 5,000, 5,000 clusters was the optimum).
For ARACNE, the tolerance parameter was optimized between 0 and 15%, as advised in [12].
The extension temperature was optimized between 37 °C and 55 °C.
The final concentration of primers and probes in each reaction was optimized between 200 nM and 500 nM.
The concentration of diluted ethanol (aqueous) was optimized between 30% and 100% v/v keeping other variables constant (BSA concentration, 1% w/v; volume of BSA solution to total ethanol ratio 1 : 1 v/v).
Hence, concentration of ethanol was optimized between 30% and 100% v/v keeping other variables constant (albumin concentration, 1% w/v; volume of BSA solution to total ethanol ratio, 1 : 1 v/v) to attain coacervation of albumin polymer to form albumin nanocarrier.
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Keyword density, the number of times a keyword or phrase appears compared to the total number of words in a page, is optimized between 2-8% according to experts.
The gas oil mass flow rate was set to be optimized between 20 and 500 kg/s, while gas oil temperature, Tg, between 520 and 800 K and catalyst temperature, (T_{text{c}},) between 700 and 1000 K.
The gas oil mass flow rate was set to be optimized between 20 and 500 kg/s as in case 1, and the catalyst mass flow rate was also set to be optimized between 20 and 500 kg/s as in case 2. The gas oil temperature, (T_{text{g}},) was set between 520 and 800 K and catalyst temperature, (T_{text{c}},) between 700 and 1000 K.
In the optimisation case 1, as propylene is maximized, the decision variable (catalyst mass flow rate) was set to be optimized between 20 and 500 kg/s, while gas oil temperature, Tg, was between 520 800 K and catalyst temperature, (T_{text{c}},) between 700 and 1000 K.
In order to calculate the IET spectra, the molecules are optimized between two Au(111) surfaces.
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