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However, this trial was not powered for this analysis, there was no fludrocortisone placebo, and the study was not blinded.
There was no effect on total mortality (chelation: 87 deaths [10%]; placebo, 93 deaths [11%]; HR, 0.93 [95% CI, 0.70-1.25]; P =.64), but the study was not powered for this comparison.
Study design allowed us to control for severity of illness but the study was not powered for mortality analysis and the case-control design may limit the generalizability of the findings.
The study was designed to be a proof-of-concept study and was not powered for statistically significant comparisons.
It should be noted that the trial was not powered for VE against clinical malaria and all analyses herein are exploratory.
The study was not powered for mortality.
The study was not powered for a noninferiority analysis.
Our study was not powered for subgroup analysis.
This exploratory study was not powered for multivariate analyses.
Furthermore, the sample size was not powered for this analysis.
However, the study size was not powered for this aim.
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