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If a PRO includes domains that are not impacted upon by the disease or its treatment, it will not be able to capture clinically meaningful change.
Although interviewer stringency leniency accounted for 9% of the variance in our study, it is generally thought that this is a relatively stable characteristic of interviewers, and is not impacted upon by training [ 40].
In particular, we note that initiation at oriC3 is not impacted upon by individual or combined Orc1/Cdc6 deletions but is abrogated by loss of expression of the Cdt1 homolog WhiP.
Thus, the names of the English stimuli had fewer syllables than the names of the Chinese stimuli, which may impact upon the level of phonological processing in Chinese and English during naming, reading and word matching but was not expected to impact upon group differences in semantic picture matching or perceptual matching that do not involve overt phonological processing.
This means that their natural behaviour is not heavily impacted upon by divers and the habitat location is not affected or altered.
Furthermore, small differences in lab-scale system setup can considerably influence energy production rates although the substrate degradation rates were not greatly impacted upon.
Ex-elite table tennis players were found to have increased levels of radiological signs of OA in the knee joint though this did not transpire through to altered levels of physical disability or knee stiffness in these players when compared with subjects from the general population suggesting that function in these players is not severely impacted upon.
So it wouldn't be possible for someone to just come and flood the network with new nodes and then be malicious because it would not impact upon the network," Lambert suggests.
McGinley believes the matter has not affected the form of either player, and has been promised the issue will not impact upon their preparations for the Ryder Cup, which begins on 26 September.
Moreover, the result is a negative one and does not impact upon the approach used by the authors.
Although aspirin exposure was not associated with an impact upon mortality in the univariate analysis (Table 2), in a multiple logistic regression analysis, treatment with aspirin was associated with a significantly lower ICU mortality compared with patients who had no aspirin exposure (OR 0.38 (0.15 to 0.96); P = 0.04).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com